Amantadine-d6 (1-Amino Adamantane-d6) - Names and Identifiers
Amantadine-d6 (1-Amino Adamantane-d6) - Physico-chemical Properties
Molecular Formula | C10H17N
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Molar Mass | 151.25 |
Storage Condition | 2-8℃ |
Amantadine-d6 (1-Amino Adamantane-d6) - Introduction
Amantadine-d6 is an important isotopically labeled compound, its chemical formula is CD3CNH2, which is an enrichment in methanol. It replaces the hydrogen atom in the methyl group with a deuterium atom, hence the name adamantane-d6 or D6 adamantane. It is a colorless liquid with special chemical properties.
Adamantane-d6 is often used as a marker compound in chemical research. Due to its special isotopic composition, it can be used as a reference substance or solvent in spectroscopic studies such as nuclear magnetic resonance (NMR). It can be used to study the structure, conformation and reaction mechanism of compounds. At the same time, adamantane-D6 is also used in biomedical research and drug research and development, used to label drug metabolism, drug transport and other processes.
The preparation of adamantane-d6 is usually achieved by treating methanol (CH3OH) with sodium deuteride (NaOD) or sodium deuterium oxide (NaOD). Where deuterium ions (D) or deuterium oxide ions (OD-) react with methyl hydrogens in methanol, replacing some or all of the hydrogen atoms with deuterium atoms, thus, adamantane-D6 was obtained.
The safety of adamantane-D6 is high, but it is still necessary to pay attention to the safety measures during operation. Due to its toxicity, direct contact with skin, eyes or inhalation of its vapors should be avoided. Appropriate protective equipment such as gloves, goggles and laboratory coats should be worn when used in the laboratory. In addition, raw materials and other chemicals in the preparation process also need to pay attention to safe operation.
Although the toxicity of adamantane-d6 is relatively low, it is still recommended to understand its safety data in detail before use, and take corresponding protective measures according to the specific situation.
Last Update:2024-04-09 21:04:16